Organic Chemistry 1

Faculteit Science and Engineering
Jaar 2019/20
Vakcode CHOC1-10
Vaknaam Organic Chemistry 1
Niveau(s) propedeuse
Voertaal Engels
Periode semester I b

Uitgebreide vaknaam Organic Chemistry 1
Leerdoelen At the end of the course, the student is able to:
1. name and draw structures of molecules containing functional groups, including conformations.
2. explain the different steps in radical halogenation reactions (assessed by being able to apply a radical halogenation on a given substrate) including the mechanism and be able to explain the chemo and regioselectivity of these reactions.
3. define the concepts of ring strain, transannular strain and eclipsed interactions (torsional strain) and apply this to the conformational analysis of (a)cyclic compounds.
4. analyse a compound with the concepts of stereochemistry, and stereo-isomerism, including chirality, which leads to a description of a compound with these terms.
5. reproduce and recognize the physical and structural properties of alcohols and ethers, their synthesis (and that of their derivatives) and their conversions.
6. carry out the straightforward retrosynthetic analyses of molecules with limited functional groups and design the appropriate synthesis schemes. The same holds for alkenes and alkynes.
7. to provide the basic concepts of cyclo-addition reactions and electrocyclisations and be able to solve synthetic problems containing these reactions. In addition, students should be able to apply the principles of electrophilic aromatic substitution, including the regioselectivity principles, and be able to explain (and predict) the regioselectivity of a given substitution reaction.
Omschrijving The aim of this part is to gain insight in a number of important principles of organic chemistry. A focal point is the understanding and the application of chemical reactions, and to get insight in the structure and reactivity of molecules. Function and reactivity of molecules is discussed in the context of materials, biologically active compounds and sustainable chemical transformations.
Uren per week
Onderwijsvorm Hoorcollege (LC), Werkcollege (T)
(Total hours of lectures: 20*2 hours, tutorials: 20*2 hours, self study: 60 hours)
Toetsvorm Schriftelijk tentamen (WE), Tussentoets (IT)
Vaksoort propedeuse
Coördinator prof. dr. M.D. Witte
Docent(en) prof. dr. J.G. Roelfes ,prof. dr. M.D. Witte
Verplichte literatuur
Titel Auteur ISBN Prijs
The book is available via the student association
Organic Chemistry: Structure and Function, 8th edition P. Vollhardt and N. Schore, 978-1-319-18771-2
Entreevoorwaarden The course unit assumes prior knowledge acquired from Molecules: structure, reactivity and Function in the Ia block of the first year Chemistry and Chemical Engineering.
The learning objectives of the course unit are required as prior knowledge for the course units practical Synthesis and Analyses 1 and Organic Chemistry 2.
Opmerkingen Written exam: max 90 points
Midterm: 10 points, pass or fail.

Final mark: (points exam + points midterm(10 or 0)))/10, rounded to half marks. It is estimated that 40% of the exam is testing whether the student can reproduce the content of the course, 40% whether the student can apply the content (solving problems), and 20% whether the student has deeper insight and abstraction. The exam plus gradin
Opgenomen in
Opleiding Jaar Periode Type
BSc Chemical Engineering 1 semester I b verplicht
BSc Chemistry 1 semester I b verplicht
BSc Courses for Exchange Students: Chemistry - Chemical Engineering - semester I b Chemistry / Chemical Engineering