Animal Experimentation

Uitgebreide vaknaam	Animal Experimentation
Leerdoelen	At the end of the course, the student is able: 1) to discuss on the ethical aspects and consequences of working with animals (both laboratory and field) during research projects 2) to describe the relevant legal framework and guidelines of working with animals (both laboratory and field) during their master phase 3) to design an experiment including: explain about the degree of standardization, construct a timeline, formulate hypotheses and choose the appropriate statistical tests to answer the questions. In addition, they are able to apply statistical methods to estimate a priori sample size 4) to choose and justify the appropriate experimental model, e.g. animal model or replacement 5) to demonstrate (practical) skills performing an animal study, upholding the guiding principles underlying the ethical and legal use of animals in scientific research, to judge animal wellbeing, to describe the 3 Rs (reduction, refinement and replacement), and to apply the practical skills needed to perform the master project.
Omschrijving	The aim of the course is to prepare students starting a master research project in which they participate in animal experimentation, with respect to methodological, practical and ethical aspects. Students will then be prepared to carry out the masterproject, under supervision of and guided by the CCD permit holder. Detailed instructions are found in Nestor, where students have to first fill in an Introduction form to be fully enrolled in the course. This course has a blended classroom format. It consists of a single contact event, whereas theoretical instruction is completely via e-learning, consisting of videos, quizzes, and assignments. Assessment is via essay questions. As the practical part, the students complete an online portfolio in collaboration with their master project instructions, and after approval of the portfolio, they receive project-specific, practical training from their supervisors. The theoretical part consists of 5 modules which guide students through the project steps as follows: (1) Preparations and ethical considerations, (2) Research question, experimental and statistical design, (3) Rules & Regulations, (4) Welfare monitoring, and (5) Scientific Publication. By in-depth reading, looking up content on the internet and by self-reflection, students will learn about scientific, practical and societal aspects of working with animals during their master project. The 5 modules contain information on •Ethics and researcher integrity in animal and human experimentation •Rules & Regulations in animal and human experimentation •Research question, experimental and statistical design •Choice of experimental model and subjects, and •Animal experimentation in practice For research involving humans, students must consult with their supervisors. From autumn 2021 onwards, students will require to purchase a small reader with study materials.
Uren per week
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC), Werkcollege (T) (LC-50 hrs, T-2 hrs, ASM-48 hrs, PRC-4 hrs, Self-study 36 hrs; Participation in the tour and the interactive lecture, or in their online equivalents where necessary, is obligatory to complete the course)
Toetsvorm	Opdracht (AST), Practisch werk (PR), Schriftelijk tentamen (WE) (WE-33%, AST-33%, PRC-33%-The homework assignment will be judged on: (1) Grammar and spelling, (2) argumentation, (3) creativity, (4) accuracy, (5) formation of opinions, (6) thinking process on ethical problems, and (7) text structure. A rubric is available to students. The course is pass / fail, and to pass, each of the above 7 items needs to be passed. If the work is insufficient students need to redo the assignment.)
Vaksoort	master
Coördinator	dr. B. Buwalda
Docent(en)	dr. B. Buwalda
Verplichte literatuur	Titel Auteur ISBN Prijs e-learning module Scientific papers
Entreevoorwaarden	Students need to have completed their Bachelor Degree in Biology, Life Sciences and Technology, Biomedical Sciences, Medicine, or Pharmacy. A supervisor approved planning of a master research projects involving human or animal experimentation is required. The course is compulsory for master students planning to work with animals during their research project. Following the course is exclusively possible in combination with a research master project involving animals or humans.
Opmerkingen
Opgenomen in	Opleiding Jaar Periode Type