Nutrition in Medicine

Uitgebreide vaknaam	Nutrition in Medicine
Leerdoelen	At the end of the course, the student is able to: 1) 1. Nutrient status and malnutrition. - define the concept and subtypes of malnutrition - describe the mechanisms underlying the development of malnutrition, and describe its consequences - understand how detection and treatment is organized in the hospital - indicate the role of micronutrient deficiency for health 2) 2. Diet and disease. - interpret the findings from nutrition epidemiology - debate the relationship between diet and type 2 diabetes mellitus - explain the association between vitamin D en chronic kidney disease 3) 3. Guidelines - explain the difference between Dietary Guidelines for prevention of disease and guidelines for Adequate Intake of Nutrients - be able to reproduce the 2015 Dutch dietary guidelines and the list of chronic diseases they are aimed at - explain how the guidelines were synthesized and which scientific criteria were used 4) 4. Diet and pharma - describe the mechanism through which high salt intake affects hypertension and renal function - give a general view on how food and pharma may interact and more specifically explain the interaction between ACE- inhibitors and salt intake 5) 5. Dietary assessment and nutrient status - list several of the most used dietary assessment methods, to explain their strengths and weaknesses, and to mention statistical approaches to evaluate these methods - list several biomarkers for dietary intake, and o explain their strengths and weaknesses 6) 6. Scientific skills - apply the recommendations of how to write a research proposal The writing skill is important if you want to obtain a PhD grant, but also if you need to write a medical ethical approval, or if you initiate projects in your future job, be it science or otherwise.
Omschrijving	Nutrition is an important determinant of health and disease. From a historical perspective nutrition in the public health domain is focused on adequate intake of micro- and macronutrients to avoid deficiency diseases. With growing affluence after the second world war, the focus shifted from deficiencies to the influence of an affluent diet and the prevention of chronic and age-related diseases , like cardiovascular and renal disease, obesity and diabetes. In the medical field, nutrition plays a role in many domains, ranging from the alleviation and prevention of disease-related malnutrition to interactions between medication and nutrition, with major consequences for health status and outcome. There is growing awareness that a healthy lifestyle is not only important in the public health domains but also in the hospital setting, in ‘preventive care’, i.e. the prevention of obesity and comorbidities in individuals who already are burdened with a chronic condition. Furthermore, the new 2015 Dutch Nutritional guidelines are fully evidence based and provide a solid basis to enhance progress in nutritional policy, dietary counseling with patients and nutrition research. From the many domains in human nutrition, we focus on several topics in this course: - dietary adequacy: micronutrient deficiencies in the general population, and recognition and treatment of malnutrition in the hospital - Interactions between food and drugs - nutritional epidemiology: the link between nutrition, nutrients, bioactive molecules and disease - nutritional guidelines In addition to topics regarding content, we focus on academic skills: - nutritional assessment, to be able to judge and conduct nutrition research (practical). - writing a research proposal. You will learn about the principles of writing a research proposal, stimulate your scientific creativity and allow you to focus more in depth on one nutrition topic (assignment).
Uren per week	40
Onderwijsvorm	Hoorcollege (LC), Opdracht (ASM), Practisch werk (PRC) (19 LC, 3 LC, T 32, ASM 45 PRC 24, self study 36)
Toetsvorm	Schriftelijk tentamen (WE), Verslag (R) (- Quality of the assignment Research Proposal (mark between 1- 10, 50%) - must be handed in to get the overall grade. If inadequate (<5.5) you need to revise. - Exam (at least 5.5 to pass the course) (50%))
Vaksoort	master
Coördinator	dr. ir. E. Corpeleijn
Docent(en)	prof. dr. S.J.L. Bakker ,dr. M.J.E. Campmans-Kuijpers ,dr. ir. E. Corpeleijn ,prof. dr. M.H. de Borst ,dr. A.D. Dekker ,prof. dr. ir. D. Kromhout ,prof. dr. G.J. Navis
Entreevoorwaarden	basic knowledge about - macro- and micronutrients, - study designs in clinical trials and epidemiology - human physiology The course is part of the Nutrition track (Adv Met Nut, NeuroBioNut, Microbiome, Nut in MEd, Brain&Cogn). for those who do not master the above knowledge completely, of who want to refresh this knowledge, supplementary material for self-study is available.
Opmerkingen	Max. capacity: 30 students. This is a MSc. Biomedical Sciences course unit: see student portal for priority regulations in place. Mandatory presence: Yes , The following criteria should be met: - Students who are absent during lectures more than 2x automatically fail the course. - Presence at the final research proposal presentations is obligatory. This course was registered last year with course code WMBM15003
Opgenomen in	Opleiding Jaar Periode Type MSc Biomedical Sciences: Biology of Ageing  (Electives (10 ECTS)) - semester I b keuze MSc Biomedical Sciences: Biology of Cancer and Immune System  (Electives ) - semester I b keuze MSc Biomedical Sciences: Biology of Food and Nutrition  ( Masters Courses) - semester I b keuzegroep MSc Biomedical Sciences: Neuroscience  (Electives (10 ECTS)) - semester I b keuze MSc Biomedical Sciences: Research  (Electives) - semester I b keuze MSc Biomedical Sciences: Science, Business and Policy  (Electives (10 ECTS)) - semester I b keuze