Current Themes in Oncology

Uitgebreide vaknaam	Current Themes in Oncology
Leerdoelen	At the end of the course, the student is able to: 1) Describe the current state-of-the-art of molecular and cellbiological mechanisms driving oncogenesis, within theme1: molecular biology of cancer 2) Describe the current state-of-the-art of molecular and cellbiological mechanisms driving oncogenesis, within theme 2: cancer epigenetics 3) Describe the current state-of-the-art of molecular and cellbiological mechanisms driving oncogenesis, within theme 3: cancer immunotherapies 4) Describe the current state-of-the-art of molecular and cellbiological mechanisms driving oncogenesis, within themes 4: cancer metabolism 5) Describe the current state-of-the-art of molecular and cellbiological mechanisms driving oncogenesis, within theme 5: cancer modeling in vitro and in vivo 6) Describe the current state-of-the-art of molecular and cellbiological mechanisms driving oncogenesis, within theme 6: cancer diagnostics 7) Describe the current state-of-the-art of molecular and cellbiological mechanisms driving oncogenesis, within theme 7: cancer current clinical therapies and ongoing trials. 8) Critically read scientific literature related the 7 defined current themes within oncology. 9) Present and discuss scientific literature related the 7 defined current themes within oncology in a journal club format
Omschrijving	Throughout this course you will learn about the current state-of-the-art of molecular and epigenetic mechanisms driving oncogenesis, in vitro and in vivo cancer models, the current state of (immune)therapeutical approaches to treat cancer patients, and the latest in cancer diagnostics. Competence to critically read scientific literature and to put this into a broad perspective. Presentation and discussion competence. The seminal “hallmarks of cancer” review series by Weinberg and colleagues will form the starting point for this course. We will focus on 7 main themes: 1) molecular biology of cancer 2) cancer epigenetics 3) cancer immunotherapies 4) cancer metabolism 5) cancer modeling in vitro and in vivo 6) cancer diagnostics 7) cancer current clinical therapies and ongoing trials. The overarching aim will be to train students in the most fundamental molecular aspects of cancer development as well as provide the latest insights into how this knowledge can be translated into clinical applicabilities. Both introductory overview lectures followed by in-depth focused seminars will be given by UMCG PIs who are key experts in these fields in order to update students with the latest state-of-the-art in the field of oncology. In groups of 2-3 students the latest discoveries in oncology will be discussed in an interactive format taking recent key papers from the field.
Uren per week	40
Onderwijsvorm	Bijeenkomst (S), Hoorcollege (LC), Opdracht (ASM)
Toetsvorm	Opdracht (AST), Schriftelijk tentamen (WE) (In order to pass the average mark needs to be >5.5)
Vaksoort	master
Coördinator	prof. dr. J.J. Schuringa
Docent(en)	prof. dr. B.M. Bakker ,prof. dr. E. Bremer ,dr. S.W.M. Bruggeman ,prof. dr. C.A.H.H. Daemen ,drs. M.C. de Bruijn ,prof. dr. S. de Jong ,prof. dr. ir. F. Foijer ,prof. dr. F.A.E. Kruyt ,prof. dr. M.G. Rots ,prof. dr. K. Thedieck ,prof. dr. ir. A.J.A. van de Sluis ,prof. dr. M.A.T.M. van Vugt
Verplichte literatuur	Titel Auteur ISBN Prijs Handouts lectures
Entreevoorwaarden	The course assumes prior knowledge from 1st year LS&T/Biology courses like Cell biology, Genetics, Biochemistry, Molecules and Reactivity; or 2nd year courses like Biology of Cancer, Haematology.
Opmerkingen	Maximum 30 students.This is a MSc. Biomedical Sciences course unit: see student portal for priority regulations in place. Aslo includes lectures from: Anke van den Berg Joost Kluiver Vincent van den Boom Gerald de Haan Edwin Bremer Alexander Dömling Frank Dekker Rudolf Fehrmann Wouter Nagengast Rainer Bischoff Ido Kema Gerwin Huls Rob Coppes This course was registered last year with course code WMBM18003
Opgenomen in	Opleiding Jaar Periode Type MSc Biomedical Sciences: Biology of Ageing  (Electives (10 ECTS)) - semester I a keuze MSc Biomedical Sciences: Biology of Cancer and Immune System  ( Masters Courses) - semester I a keuzegroep MSc Biomedical Sciences: Biology of Food and Nutrition  (Electives (10 ECTS)) - semester I a keuze MSc Biomedical Sciences: Neuroscience  (Electives (10 ECTS)) - semester I a keuze MSc Biomedical Sciences: Research  (Electives) - semester I a keuze MSc Biomedical Sciences: Science, Business and Policy  (Electives (10 ECTS)) - semester I a keuze