Organic Chemistry 1

Faculteit Science and Engineering
Jaar 2021/22
Vakcode WBCH013-05
Vaknaam Organic Chemistry 1
Niveau(s) propedeuse
Voertaal Engels
Periode semester I b

Uitgebreide vaknaam Organic Chemistry 1
Leerdoelen At the end of the course, the student is able to:
1) name and draw structures of molecules containing functional groups, including conformations and different projections.
2) explain the different steps in radical halogenation reactions including the mechanism and be able to explain the chemo
and regioselectivity of these reactions.
3) define the concepts of ring strain, transannular strain and eclipsed interactions (torsional strain) and apply this to the
conformational analysis of (a)cyclic compounds.
4) analyse a compound with the concepts of stereochemistry, and stereo-isomerism,and apply these concepts in simple
5) recognize the following functional groups: alcohols, ethers, alkenes, alkynes, dienes and aromatic compounds and can
reproduce their effect on the physical and structural properties.
6) reproduce the reactions that alcohols, ethers, alkenes, alkynes, dienes and aromatic compounds undergo and can
apply this knowledge in synthesis routes, including functional group transformations and cycloaddition reactions.
7) carry out the straightforward retrosynthetic analyses of molecules with limited functional groups and design appropriate
synthesis schemes for these molecules.
8) apply the principles of electrophilic aromatic substitution, including the regioselectivity principles, and be able to explain
(and predict) the regioselectivity of a given substitution reaction.
Omschrijving The aim of this part is to gain insight in a number of important principles of organic chemistry. A focal point is the understanding and
the application of chemical reactions, and to get insight in the structure and reactivity of molecules. Function and reactivity of
molecules is discussed in the context of materials, biologically active compounds and sustainable chemical transformations.
Uren per week
Onderwijsvorm Hoorcollege (LC), Practisch werk (PRC), Werkcollege (T)
(Total hours of lectures: 20*2 hours, tutorials: 20*2 hours, self study: 60 hours)
Toetsvorm Schriftelijk tentamen (WE), Tussentoets (IT)
Vaksoort propedeuse
Coördinator prof. dr. M.D. Witte
Docent(en) prof. dr. T. Kudern√°c ,prof. dr. M.D. Witte
Verplichte literatuur
Titel Auteur ISBN Prijs
Organic Chemistry: Structure and Function, 8th edition P. Vollhardt and N. Schore 978-1-319-18771-2
Entreevoorwaarden The course unit assumes prior knowledge acquired from Molecules: Structure, Reactivity and Function in the Ia block of the first

year Chemistry and Chemical Engineering.
The learning objectives of the course unit are required as prior knowledge for the course units practical Synthesis and Analyses 1
and Organic Chemistry 2.
Opmerkingen Written exam: max 90 points
Midterm: 10 points, pass or fail.

Final mark: The grade will be calculated either by (number of points exam + pass/fail midterm)/10 or by (number of points exam)/90*10, whichever gives the highest grade. The students will receive ten points when passing the midterm and zero points when they fail. To pass the midterm, they will have to get 55 out of the 100 points.

It is estimated that 40% of the exam is testing whether the student can reproduce the content of the course, 40% whether the student can apply the content (solving problems), and 20% whether the student has deeper insight and abstraction.

This course was registered last year with course code CHOC1-10
Opgenomen in
Opleiding Jaar Periode Type
BSc Chemical Engineering 1 semester I b verplicht
BSc Chemistry  ( Core programme) 1 semester I b verplicht
BSc Courses for Exchange Students: Chemistry - Chemical Engineering - semester I b