Faculteit Science and Engineering
Jaar 2020/21
Vakcode WBBY058-05
Vaknaam Metabolism
Niveau(s) propedeuse
Voertaal Engels
Periode semester II b

Uitgebreide vaknaam Metabolism
Leerdoelen At the end of the course, the student is able to:
- Explain the principles of cellular metabolism (integration of metabolic pathways, role of energy and redox cofactors, metabolite balancing, etc.);
- Explain the regulation mechanisms of metabolism (including kinetics and thermodynamics);
- Apply knowledge of the main biochemical pathways in primary carbon and energy metabolism (glycolysis, gluconeogenesis, citric acid cycle, respiration (chemiosmotic theory), pentose phosphate pathway, glycogen and lipid metabolism), and about the existence of other pathways;
- Describe connections of metabolic failure with diseases, and understand relevance of metabolism with biotechnology;
- Explain the principles of human metabolism on the organismal level.
Omschrijving In this course, the students learn how cells build and preserve themselves, at the biochemical level. Specifically, they will learn the principles how cells absorb, store and recruit energy and nutrients, and convert these nutrients into cell components via metabolic pathways. As careful coordination of these biochemical processes is crucial for cellular function, also the respective regulation mechanisms occurring at various levels will be taught. Finally, in a few lectures, also the key principles of organismal metabolism will be covered.
Uren per week
Onderwijsvorm Hoorcollege (LC), Practisch werk (PRC), Werkcollege (T)
(LC-24hr; T-4hr; PRC-6hr; Self-study 106 hrs)
Toetsvorm Meerkeuze toets (MC), Schriftelijk tentamen (WE)
(WE-100% - Digital exam consisting of multiple choice and open questions. See remarks.)
Vaksoort propedeuse
Coördinator prof. dr. M. Heinemann
Docent(en) prof. dr. B.M. Bakker ,prof. dr. M. Heinemann
Verplichte literatuur
Titel Auteur ISBN Prijs
Biochemistry (2015) 8th ed. Jeremy M. Berg, Lubert Stryer, John L. Tymoczko, Gregory J. Gatto
Slides from lectures M. Heinemann, B. Bakker
Entreevoorwaarden Basic molecular and cell biology, Molecules of life

Biology and Life Science & Technology (old curriculum) course units are only accessible for students of those degree programmes. Students from other degree programmes who would like to participate in Biology course units are obliged to contact one of the academic advisors before registration. After this contact, students have to request admission from the Board of Examiners Biology/Life Science & Technology. Failing to follow this procedure results in immediate unenrollment without prior notification.
Opmerkingen The tutorials and the computer practicals are obligatory; only a single one out of the 5 practice elements (i.e. tutorials/computer practicals) can be missed, only for good reasons, such as, for instance, due to illness, and only when notified PRIOR to the respective tutorial/computer practical (via Presence will be checked.

Digital examination is made up of two parts: The first examination consists of multiple choice questions. Only students who score at least 35% correct (adjusted for chance) on the multiple choice questions are allowed to do the second part of the examination with the open question exam. Students who score less than 35% in part 1, fail the course. The grade for the course is solely based on the score of part 2. In case, students do not obtain at least a 6.0, they need to re-do part 1 and part 2 in the re-exam. For the re-exam the same rules apply.

Dit vak had vorig jaar vakcode WPLS18013
Opgenomen in
Opleiding Jaar Periode Type
BSc Biology - Year 1 1 semester II b verplicht BN/BMS/ML
BSc Biology: major Behaviour and Neurosciences 1 semester II b verplicht
BSc Biology: major Biomedical Sciences 1 semester II b verplicht
BSc Biology: major Integrative Biology  (Semester 2, BN/BMS/ML route) 1 semester II b verplicht
BSc Biology: major Molecular Life Sciences 1 semester II b verplicht