Organic Synthesis, Methods and Strategy 1

Uitgebreide vaknaam	Organic Synthesis, Methods and Strategy 1
Leerdoelen	Upon completion of this course, the student should be able to: 1. to use, install and remove protecting groups in organic synthesis 2. to select the methods and differentiate the reactivity associated with different functional group and functional group interconversion and apply this knowledge in the synthesis of target organic molecules. 3. to distinguish, contrast and properly apply different methods for oxidation and reduction processes. 4. to use elementary organometallic chemistry in organic synthesis, for pericyclic reactivity, as well as in asymmetric catalysis. 5. to recognize rearrangements products and apply them in the synthesis 6. identify carbonyl chemistry and relate it to the synthesis of organic molecules 7. to describe specifics chemistry with organic molecules containing B, Si, P and S atoms 8. to interpret and discuss different mechanisms, write a reasonable organic reaction mechanism and apply the knowledge of mechanisms to new reactions.
Omschrijving	This is a specialized course to build on prior study in synthetic organic chemistry, with the aim to develop a more advanced understanding and synthetic strategies in organic chemistry. The course is about the reactivity of organic molecules, and how this reactivity is used in the synthesis of important and interesting compounds using modern synthetic methods. The topics covered by this course are: selectivity in synthesis, reductions/oxidations/protecting groups, enolate chemistry, modern aldol reactions, copper-catalyzed carbon-carbon bond formation, palladium-catalyzed reactions, the organic chemistry using B, Si, P and S; controlling the double bond geometry, pericyclic reactions and their applications in organic synthesis; rearrangements reactions.
Uren per week
Onderwijsvorm	Bijeenkomst (S), Opdracht (ASM) (The course will be given as interactive lectures)
Toetsvorm	Schriftelijk tentamen (WE)
Vaksoort	master
Coördinator	prof. dr. S. Harutyunyan
Docent(en)	prof. dr. S. Harutyunyan ,prof. dr. ir. A.J. Minnaard
Verplichte literatuur	Titel Auteur ISBN Prijs Organic Chemistry Clayden, Greeves, Warren - Oxford University Press, 2012 978-0-19-927029-3 €  60,00
Entreevoorwaarden
Opmerkingen	The course is given in Dutch or in English depending on the presence of foreign students.
Opgenomen in	Opleiding Jaar Periode Type MSc Chemical Engineering  ( Catalysis and Green Chemistry) - semester II a verplicht MSc Chemistry  (Catalysis and Green Chemistry) - semester II a verplicht MSc Erasmus Mundus Chemistry (TCCM)  (Electives) 1 semester II a keuze MSc Nanoscience  (Optional Courses) - semester II a keuze