Grant for Jan Jongbloed from Netherlands Heart Foundation
Jan Jongbloed and co-applicant Peter van Tintelen have been awarded a grant by the Netherlands Heart Foundation to implement their proposal "Exome sequencing: an unprecedented opportunity to maximize mutation yields and identify novel disease genes in inherited cardiomyopathies". In this project 50 cardiomyopathy families will be analysed by applying exome sequencing to identify the underlying disease gene. If this leads to the identification of new disease gene(s), then DNA samples from a cohort of ~250 additional cardiomyopathy patients will be screened for mutations in these candidate genes. In addition, immunohistochemical analysis on myocardial biopsies will be performed to confirm the functional consequences of the mutations identified. The project is a cooperation between the UMCG Departments of Genetics (Jongbloed, van Tintelen, Sinke, Hofstra), Cardiology (van den Berg, de Boer) and Pathology (Suurmeijer).
Last modified: | 14 December 2023 08.16 a.m. |
More news
-
18 April 2024
PET-scan expert Jan Pruim benoemd tot Officier in Orde van Oranje Nassau
Hoogleraar medische beeldvorming Jan Pruim is bij zijn afscheid van het UMCG benoemd tot Officier in de Orde van Oranje Nassau. De koninklijke versierselen werden hem op woensdag 17 april uitgereikt door burgemeester Koen Schuiling van de gemeente...
-
27 March 2024
UG/UMCG researchers receive prestigious research grant
RUG/UMCG scientists Mark Hipp, Bart Eggen, Moniek Tromp and Marleen Kamperman, along with colleagues, are involved in four of seven Dutch science consortia.
-
26 March 2024
Preventing the next depression
Marie-José van Tol, Professor of 'Mood and Cognition’, studies what people who are prone to depression can do themselves in order to prevent recurrence.