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MR perfusion in the detection of myocardial ischemia

09 December 2009

PhD cermony: D.D. Lubbers, 13.15 uur, Academiegebouw, Broerstraat 5, Groningen

Proefschrift: MR perfusion in the detection of myocardial ischemia

Promotor(s): prof.dr. M. Oudkerk

Faculteit: Medische Wetenschappen

Contact: via de persvoorlichters van het UMCG, tel. 050-361 2200, e-mail: voorlichting bvl.umcg.nl

This thesis focuses on MR perfusion in the detection of myocardial ischemia and used protocols in this respect. In patients with no prior myocardial infarction an adenosine “stress”-only technique can reliably exclude significant myocardial ischemia in a large patient group in a protocol time of only 15-20 minutes. Using systematic reading criteria for a visual analysis of perfusion images considerably improves agreement with an expert reader. In a post-infarct setting improvements in time can be achieved by reducing post-processing of a stack of short-axis cine images by analysing only every second short-axis series for global left ventricular functional parameter assessment. In this respect, specificity of a dobutamine stress MR examination can be increased by performing a perfusion sequence on peak dose dobutamine. For imaging at higher heart rates, a TSENSE first-pass perfusion sequence may play a role to maintain enough spatial coverage.
Last modified:15 September 2017 3.39 p.m.
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