PhD Ceremony: E.J. Blom, 14.45 uur, Academiegebouw, Broerstraat 5, Groningen
Dissertation: Computational genomics of prokaryotes
Promotor(s): prof.dr. O.P. Kuipers, prof.dr. J.B.T.M. Roerdink
Faculty: Mathematics and Natural Sciences
Contact: Evert-Jan Blom, tel. 0317-46 6866, e-mail: firstname.lastname@example.org
The use of DNA microarray-based transcription proﬁling techniques is providing large quantities of genome-wide data on gene-expression patterns. This transcriptome data provide researchers with alternative ways to address and interpret biological questions in a functional and regulatory context. Although its application is ubiquitous in various areas of research, the analysis of the data that result from these experiments still remain a challenge.
The main research theme of the thesis of Evert-Jan Blom is the development of analytical software approaches and tools to analyze, visualize and exploit the information contained in global gene expression data. He has addressed the analysis of transcriptome data using various applications that were developed in-house; ranging from functional enrichment analyses, identiﬁcation and visualization of regulatory elements, annotation of clustering results and the inference of putative gene functions using gene expression data.
His last experimental chapter describes the results of the analysis of a large time-resolved transcriptome dataset (40 time points) of the model bacterium B.subtilis using several of the earlier described tools. The most remarkable outcome of his analysis is the occurrence of stress during the transitions between the different growth phases. These stress responses are not induced by added external stimuli or artiﬁcially induced starvation conditions, but are naturally occurring during the growth phases of B. subtilis.
Zito Ysenbaert is the first winner of the Gerrit Krol Award, the University of Groningen (UG) essay competition.
On Friday 14 June, the University of Groningen will be awarding honorary doctorates to Prof. Titia de Lange and Dr Philipp Blom. This academic ceremony is part of the 81st lustrum that takes place from 5 to 15 June 2019. During the ceremony, Prof. Elmer...
More than 200 researchers and their teams can begin to work on social and scientific issues in close collaboration with public and private parties. This close collaboration will take place in 17 research projects.