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Characterization of key proteins involved in the SCB signalling system for secondary metabolism in streptomyces coelicolor

27 November 2009

PhD ceremony: mw. N. Hsiao, 13.15 uur, Academiegebouw, Broerstraat 5, Groningen

Thesis: Characterization of key proteins involved in the SCB signalling system for secondary metabolism in streptomyces coelicolor

Promotor(s): prof.dr. L. Dijkhuizen

Faculty: Mathematics and Natural Sciences

Contact: Nai-Hua Hsiao, tel. +31 (0) 50-363 2201, e-mail: n.hsiao@rug.nl

Nai-Hua Hsiao investigated the enzymatic role of ScbA in the biosynthetic pathway of γ-butyrolactones in Streptomyce coelicolor which is strongly suggested by active site mutagenesis. In addition to the enzymatic function, ScbA may also possess a role in the regulation of antibiotic production and morphological differentiation. It seems that ScbA has dual function in S. coelicolor concludes Hsiao.

Last modified:15 September 2017 3.38 p.m.
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