PhD ceremony: H.P. Pérez de Vladar, 13.15 uur, Academiegebouw, Broerstraat 5, Groningen
Thesis: Stochasticity and variability in the dynamics and genetics of populations
Promotor(s): prof. I. Pen, prof. F. Weissing
Faculty: Mathematics and Natural Sciences
Harold Perez de Vladar has set a new methodology to understand and predict the evolution of traits that are affected by many genes. Typically we need to know details of the genetic composition of those traits, which in practice are difficult to measure, and any mathematical treatment is hard. But his research provides a neat mathematical methodology that overcomes many of these limitations.
Population dynamics is a temporal description of the number of individuals in a population. Many models exist that quantify the process of population growth. In his thesis Perez de Vladar approaches the subject with the goal of bringing together several of these models into a simple general one. Although carrying capacity is often invoked as a mechanism for density dependence (the regulation of growth rates according to the population's size), the general version does not resort to this mechanism. For certain conditions, however, carrying capacities emerge. Other conditions lead to populations that explode in size. However, certain kind of random perturbations can drive the dynamics of the population in a way that they mimic density dependence. This finding of Perez de Vladar provides alternative testable explanations for the demographic diversity in natural populations.
The evolution of quantitative traits depends on the frequencies of many alleles involved, which can rarely be measured. Perez de Vladar developed an approximation borrowing methods from statistical mechanics to predict the dynamics of observable quantities, such as the mean and variance of a trait. Populations are shown to evolve to an entropy maximum, subject to constraints on the expected values of observable quantities. The method gives the equilibrium state exactly and is accurate even when there are abrupt changes in directional or stabilizing selection. Applications to selection for multiple characters are also studied by Perez de Vladar, and data of evolving traits of the common frog Rana temporaria is analyzed in order to gain insights on the limitations of the method. He also initiates a discussion on the interpretation of entropy in evolution as information created by natural selection.
The team developed a protocol to share delicate information via a biological QR-code.
Moniek Tromp and Marleen Kamperman share a lot in common. Both are young professors of chemistry at the
Zernike Institute for Advanced Materials (ZIAM).Both joined the UG in 2018. Both are engaged in developing new materials. Both enjoy promoting science...
After two years of hard work, the Groningen Top Dutch Solar Racing team has arrived in Australia. The team consists of students of the Hanze University of Applied Sciences, University of Groningen, and secondary vocational education (MBO) and is currently...