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Caenorhabditis elegans models for protein misfolding diseases

16 September 2009

PhD ceremony: T.J. van Ham, 16.15 uur, Academiegebouw, Broerstraat 5, Groningen

Thesis: Caenorhabditis elegans models for protein misfolding diseases

Promotor(s): prof. R.M.W. Hofstra

Faculty: Medical Sciences


Many neurodegenerative diseases are associated with the formation of protein inclusions in the brain. Most of the inclusions contain disease specific misfolded proteins such as alpha -synuclein in Parkinson’s disease, and polyglutamine (polyQ)-protein in polyQ diseases. Finding and elucidating the molecular pathways involved in toxic protein aggregation related to disease will help understanding these diseases.


Last modified:15 September 2017 3.39 p.m.

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