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Characterization of CLC transporters

21 September 2009

PhD ceremony: H. Moradi, 11.00 uur, Academiegebouw, Broerstraat 5, Groningen

Thesis: Characterization of CLC transporters

Promotor(s): prof. J.T.M. Elzenga

Faculty: Mathematics and Natural Sciences


In higher plants anion channels present in various tissues and cell types, play importants roles. One of several protein families with anion channel function, is the Chloride Channel (CLC) family. Seven CLC genes are identified in the Arabidopsis genome. The main aim of the research of Hossein Moradi was to physiologically characterize Arabidopis thaliana CLC proteins and to acquire knowledge on the position of CLC proteins in the complex network of membrane transport and solute fluxes. He suggests that the main role of the CLC proteins is to function as electrical short circuits, which play an important role in energizing the membranes. A role in NO3 - and CL- homeostasis seems of minor importance. Another important issue is the intracellular localization of these proteins. Knowledge on the whereabouts of these proteins in the cell has important implications on their functions. Although the results, published in the present literature are in agreement with the ideas of the function of the CLC protein, care must still be taken with the interpretation of the fluorescence data on the localization of the CLC proteins. The published data seems to lack important controls.


Last modified:15 September 2017 3.39 p.m.

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