Seminarium: Toru Tanimori, Kyoto University, Japan
|Wanneer:||wo 15-02-2012 om 11:00|
PET and SPECT achieved great success at a molecular imaging and nuclear medicine. These detector, however, have the energy limitation, which is a problem in a design of new molecular imaging reagents. We have developed an Electron-Tracking Compton Camera (ETCC) for medical imaging due to its wide energy dynamic range (200 - 1500 keV) and wide field of view (FOV, 3 str). Thus this camera has a potential of developing the new reagents for molecular imaging. Until now we have carried out several imaging reagent studies using those features of ETCCas follows: (1) F-18-FDG (511 keV) and I-131-MIBG (364 keV) simultaneous imaging for double clinical tracer imaging, (2) Zn-65-porphyrin (1116 keV) imaging for high energy gamma-ray imaging and, (3)imaging of some minerals (Mn-54, Zn-65, Fe-59) in mouse and so on.
In addition, ETCC can image continuum spectral gamma-rays. Radiation therapy with proton and heavy-ion beams has been established. ETCC has a potential of real-time monitoring of the Bragg peak location by imaging the continuum prompt gamma rays emitted from the proximity of the Bragg peak. We carried out the water phantom experiment using 140 MeV proton beam, and successfully obtained the images of both 511 keV and continuum high energy gamma rays (800-2000keV). Here better correlation of the latter image to the Bragg peak has been observed.