Skip to ContentSkip to Navigation
About us Latest news Press information

Jansen, Prof. Ritsert

Ritsert Jansen
Ritsert Jansen

Ritsert Jansen is professor of bio-informatics and head of the Groningen Bioinformatics Centre. Jansen studied mathematics at the University of Groningen and then went to work for a research institute in Wageningen. The advent of new biomolecular tools led him to develop new statistical tools for mapping QTLs (‘quantitative trait loci’, stretches of DNA containing or linked to the genes that underlie a quantitative trait) in plants, and this research formed the basis of his PhD thesis. In 2002, he returned to the University of Groningen where he holds a joint appointment at the Faculty of Science and Engineering and the Faculty of Medical Sciences as a professor of bioinformatics. At present, his research group is interested in designing, modelling and analysing quantitative biomolecular experiments on populations, using ‘genetic genomics’ strategies that combine the merits of genetics with the power of genomics.

Jansen is also a ‘Dean of Talent Development’ at the University of Groningen. As an acclaimed researcher he likes to give young colleagues a helping hand. In 2011 his book Developing a Talent for Science was published by Cambridge University Press, in which he discusses the stressful life of modern scientists in an increasingly competitive academic environment. ‘You are an entrepreneur in the land of research’, says Jansen. ‘In the past you would be welcomed to your new research place with a big bag of money, but nowadays scientists have to gather their own funds by winning grants.’ In 2013 Funding your career in Science was released by Cambridge University Press.

As Dean, Jansen is involved in matters such as training courses for academics in the field of applying for grants and holding presentations, as well as in the Grants Week, a large event for researchers seeking to acquire grants.

Article UG
Article UG

Contact and further information



Zych, K., Gort, G., Maliepaard, C. A., Jansen, R. C., & Voorrips, R. E. (2019). FitTetra 2.0-improved genotype calling for tetraploids with multiple population and parental data support. Bmc Bioinformatics, 20, [148].
Prins, P., Smant, G., Arends, D., Mulligan, M. K., Williams, R. W., & Jansen, R. C. (2019). Systems Genetics for Evolutionary Studies. In M. Anisimova (Ed.), Evolutionary Genomics (pp. 635-652). (Methods in Molecular Biology; Vol. 1910). Springer.


Zych, K., Snoek, L. B., Elvin, M., Rodriguez, M., van der Velde, K. J., Arends, D., Westra, H-J., Swertz, M. A., Poulin, G., Kammenga, J. E., Breitling, R., Jansen, R. C., & Li, Y. (2017). reGenotyper: Detecting mislabeled samples in genetic data. PLoS ONE, 12(2), [e0171324].


Westra, H-J., Arends, D., Esko, T., Peters, M. J., Schurmann, C., Schramm, K., Kettunen, J., Yaghootkar, H., Fairfax, B. P., Andiappan, A. K., Li, Y., Fu, J., Karjalainen, J., Platteel, M., Visschedijk, M., Weersma, R. K., Kasela, S., Milani, L., Tserel, L., ... Franke, L. (2015). Cell Specific eQTL Analysis without Sorting Cells. PLoS genetics, 11(5), [1005223].
Fehrmann, R. S. N., Karjalainen, J. M., Krajewska, M., Westra, H-J., Maloney, D., Simeonov, A., Pers, T. H., Hirschhorn, J. N., Jansen, R. C., Schultes, E. A., van Haagenl, H. H. H. B. M., de Vries, E. G. E., te Meerman, G., Wijmenga, C., van Vugt, M. A. T. M., & Franke, L. (2015). Gene expression analysis identifies global gene dosage sensitivity in cancer. Nature Genetics, 47(2), 115-125.
Zych, K., Li, Y., van der Velde, J. K., Joosen, R. V. L., Ligterink, W., Jansen, R. C., & Arends, D. (2015). Pheno2Geno: High-throughput generation of genetic markers and maps from molecular phenotypes for crosses between inbred strains. Bmc Bioinformatics, 16(1), [51].
van der Graaf, A., Wardenaar, R., Neumann, D. A., Taudt, A., Shaw, R. G., Jansen, R. C., Schmitz, R. J., Colome-Tatche, M., & Johannes, F. (2015). Rate, spectrum, and evolutionary dynamics of spontaneous epimutations. Proceedings of the National Academy of Sciences of the United States of America, 112(21), 6676-6681.
Prins, P., de Ligt, J., Tarasov, A., Jansen, R. C., Cuppen, E., & Bourne, P. E. (2015). Toward effective software solutions for big biology. Nature Biotechnology, 33(7), 686-687.


Cortijo, S., Wardenaar, R., Colome-Tatche, M., Gilly, A., Etcheverry, M., Labadie, K., Caillieux, E., Hospital, F., Aury, J-M., Wincker, P., Roudier, F., Jansen, R. C., Colot, V., & Johannes, F. (2014). Mapping the Epigenetic Basis of Complex Traits. Science, 343(6175), 1145-1148.
Rintisch, C., Heinig, M., Bauerfeind, A., Schafer, S., Mieth, C., Patone, G., Hummel, O., Chen, W., Cook, S., Cuppen, E., Colomé Tatché, M., Johannes, F., Jansen, R. C., Neil, H., Werner, M., Pravenec, M., Vingron, M., & Hubner, N. (2014). Natural variation of histone modification and its impact on gene expression in the rat genome. Genome Research, 24(6), 942-953.
Pino Del Carpio, D., Basnet, R. K., Arends, D., Lin, K., De Vos, R. C. H., Muth, D., Kodde, J., Boutilier, K., Bucher, J., Wang, X., Jansen, R., & Bonnema, G. (2014). Regulatory network of secondary metabolism in Brassica rapa: insight into the glucosinolate pathway. PLoS ONE, 9(9), [e107123].
Snoek, L. B., Joeri van der Velde, K., Li, Y., Jansen, R. C., Swertz, M. A., & Kammenga, J. E. (2014). Worm variation made accessible: Take your shopping cart to store, link, and investigate! Worm, 3(2), [e28357].
Velde, K. J. V. D., Haan, M. D., Zych, K., Arends, D., Snoek, L. B., Kammenga, J. E., Jansen, R. C., Swertz, M. A., & Li, Y. (2014). WormQTL(HD)-a web database for linking human disease to natural variation data in C. elegans. Nucleic Acids Research, 42(D1), D794-D801.


Joosen, R. V. L., Arends, D., Li, Y., Willems, L. A. J., Keurentjes, J. J. B., Ligterink, W., Jansen, R. C., & Hilhorst, H. W. M. (2013). Identifying Genotype-by-Environment Interactions in the Metabolism of Germinating Arabidopsis Seeds Using Generalized Genetical Genomics. Plant Physiology, 162(2), 553-566.
Westra, H-J., Peters, M. J., Esko, T., Yaghootkar, H., Schurmann, C., Kettunen, J., Christiansen, M. W., Fairfax, B. P., Schramm, K., Powell, J. E., Zhernakova, A., Zhernakova, D. V., Veldink, J. H., Van den Berg, L. H., Karjalainen, J., Withoff, S., Uitterlinden, A. G., Hofman, A., Rivadeneira, F., ... Hoen, P. A. C. . (2013). Systematic identification of trans eQTLs as putative drivers of known disease associations. Nature Genetics, 45(10), 1238-1243.
Snoek, L. B., Van der Velde, K. J., Arends, D., Li, Y., Beyer, A., Elvin, M., Fisher, J., Hajnal, A., Hengartner, M. O., Poulin, G. B., Rodriguez, M., Schmid, T., Schrimpf, S., Xue, F., Jansen, R. C., Kammenga, J. E., & Swertz, M. A. (2013). WormQTL-public archive and analysis web portal for natural variation data in Caenorhabditis spp. Nucleic Acids Research, 41(D1), D738-D743.


Durrant, C., Swertz, M. A., Alberts, R., Arends, D., Moeller, S., Mott, R., Prins, P., van der Velde, K. J., Jansen, R. C., & Schughart, K. (2012). Bioinformatics tools and database resources for systems genetics analysis in mice-a short review and an evaluation of future needs. Briefings in Bioinformatics, 13(2), 135-142.
Colomé Tatché, M., Cortijo, S., Wardenaar, R., Monteiro Morgado, L., Lahouze, B., Sarazin, A., Etcheverry, M., Martin, A., Feng, S., Duvernois-Berthet, E., Labadie, K., Wincker, P., Jacobsen, S. E., Jansen, R. C., Colot, V., & Johannes, F. (2012). Features of the Arabidopsis recombination landscape resulting from the combined loss of sequence variation and DNA methylation. Proceedings of the National Academy of Sciences of the United States of America, 109(40), 16240-16245.
Prins, P., Smant, G., & Jansen, R. C. (2012). Genetical Genomics for Evolutionary Studies. Methods in Molecular Biology, 856, 469-485.
Demirkan, A., van Duijn, C. M., Ugocsai, P., Isaacs, A., Pramstaller, P. P., Liebisch, G., Wilson, J. F., Johansson, A., Rudan, I., Aulchenko, Y. S., Kirichenko, A. V., Janssens, A. C. J. W., Jansen, R. C., Gnewuch, C., Domingues, F. S., Pattaro, C., Wild, S. H., Jonasson, I., Polasek, O., ... EUROSPAN Consortium (2012). Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations. PLoS genetics, 8(2), [e1002490].
Lendvai, Á., Johannes, F., Grimm, C., Eijsink, J. J. H., Wardenaar, R., Volders, H. H., Klip, H. G., Hollema, H., Jansen, R. C., Schuuring, E., Wisman, G. B. A., & van der Zee, A. G. J. (2012). Genome-wide methylation profiling identifies hypermethylated biomarkers in high-grade cervical intraepithelial neoplasia. Epigenetics, 7(11), 1268-1278.
Diekstra, F. P., Saris, C. G. J., van Rheenen, W., Franke, L., Jansen, R. C., van Es, M. A., van Vught, P. W. J., Blauw, H. M., Groen, E. J. N., Horvath, S., Estrada, K., Rivadeneira, F., Hofman, A., Uitterlinden, A. G., Robberecht, W., Andersen, P. M., Melki, J., Meininger, V., Hardiman, O., ... Brown Jr., R. H. (2012). Mapping of Gene Expression Reveals CYP27A1 as a Susceptibility Gene for Sporadic ALS. PLoS ONE, 7(4), [e35333].
Zych, K., Arends, D., & Jansen, R. (2012). Pheno2geno; generating genetic markers and maps from molecular phenotypes.
Neto, E. C., Keller, M. P., Broman, A. F., Attie, A. D., Jansen, R. C., Broman, K. W., & Yandell, B. S. (2012). Quantile-Based Permutation Thresholds for Quantitative Trait Loci Hotspots. Genetics, 191(4), 1355-1365.
Fu, J., Wolfs, M. G. M., Deelen, P., Westra, H. J., Fehrmann, R. S. N., te Meerman, G., Buurman, W. A., Rensen, S. S. M., Groen, H., Weersma, R. K., van den Berg, L. H., Veldink, J., Ophoff, R. A., Snieder, H., van Heel, D., Jansen, R. C., Hofker, M. H., Wijmenga, C., & Franke, L. (2012). Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS genetics, 8(1), [e1002431].
Joosen, R. V. L., Arends, D., Willems, L. A. J., Ligterink, W., Jansen, R. C., & Hilhorst, H. W. M. (2012). Visualizing the Genetic Landscape of Arabidopsis Seed Performance. Plant Physiology, 158(2), 570-589.
Arends, D., van der Velde, K. J., Prins, P., Broman, K. W., Moller, S., Jansen, R. C., & Swertz, M. A. (2012). xQTL workbench: a scalable web environment for multi-level QTL analysis. Bioinformatics, 28(7), 1042-1044.


Trelles, O., Prins, P., Snir, M., & Jansen, R. C. (2011). Big data, but are we ready? Nature Reviews Genetics, 12(3), 224-224.
Roux, F., Colomé-Tatché, M., Edelist, C., Wardenaar, R., Guerche, P., Hospital, F., Colot, V., Jansen, R. C., & Johannes, F. (2011). Genome-Wide Epigenetic Perturbation Jump-Starts Patterns of Heritable Variation Found in Nature. Genetics, 188(4), 1015-1017.
Westra, H-J., Jansen, R. C., Fehrmann, R. S. N., te Meerman, G. J., van Heel, D., Wijmenga, C., Franke, L., & te Meerman, G. (2011). MixupMapper: correcting sample mix-ups in genome-wide datasets increases power to detect small genetic effects. Bioinformatics, 27(15), 2104-2111.
Scheltema, R. A., Jankevics, A., Jansen, R. C., Swertz, M. A., & Breitling, R. (2011). PeakML/mzMatch: A File Format, Java Library, R Library, and Tool-Chain for Mass Spectrometry Data Analysis. Analytical Chemistry, 83(7), 2786-2793.
Seinen, E., Burgerhof, J. G., Jansen, R. C., & Sibon, O. C. (2011). RNAi-induced off-target effects in Drosophila melanogaster: frequencies and solutions. Briefings in Functional Genomics, 10(4), 206-214.
Fehrmann, R. S. N., Jansen, R. C., Veldink, J. H., Westra, H. J., Arends, D., Bonder, M. J., Fu, J., Deelen, P., Groen, H., Smolonska, J., Weersma, R. K., Hofstra, R. M. W., Buurman, W. A., Rensen, S., Wolfs, M. G. M., Platteel, M., Zhernakova, A., Elbers, C. C., Festen, E. A., ... Franke, L. (2011). Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS genetics, 7(8), [1002197].


Johannes, F., Wardenaar, R., Colomé Tatché, M., Mousson, F., de Graaf, P., Mokry, M., Guryev, V., Timmers, H. T. M., Cuppen, E., & Jansen, R. C. (2010). Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq. Bioinformatics, 26(8), 1000-1006.
Li, Y., Tesson, B. M., Churchill, G. A., & Jansen, R. C. (2010). Critical reasoning on causal inference in genome-wide linkage and association studies. Trends in Genetics, 26(12), 493-498.
Tesson, B. M., Breitling, R., & Jansen, R. C. (2010). DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules. Bmc Bioinformatics, 11(1), 497-1-497-9. [497].
Li, Y., Breitling, R., Snoek, L. B., van der Velde, K. J., Swertz, M. A., Riksen, J., Jansen, R. C., & Kammenga, J. E. (2010). Global Genetic Robustness of the Alternative Splicing Machinery in Caenorhabditis elegans. Genetics, 186(1), 405-U620.
Seinen, E., Burgerhof, J. G. M., Jansen, R. C., & Sibon, O. C. M. (2010). RNAi Experiments in D. melanogaster: Solutions to the Overlooked Problem of Off-Targets Shared by Independent dsRNAs. PLoS ONE, 5(10), [13119].
Arends, D., Prins, P., Jansen, R. C., & Broman, K. W. (2010). R/qtl: high-throughput multiple QTL mapping. Bioinformatics, 26(23), 2990-2992.
Nieselt, K., Battke, F., Herbig, A., Bruheim, P., Wentzel, A., Jakobsen, O. M., Sletta, H., Alam, M. T., Merlo, M. E., Moore, J., Omara, W. A. M., Morrissey, E. R., Juarez-Hermosillo, M. A., Rodriguez-Garcia, A., Nentwich, M., Thomas, L., Iqbal, M., Legaie, R., Gaze, W. H., ... Morrisey, E. R. (2010). The dynamic architecture of the metabolic switch in Streptomyces coelicolor. BMC Genomics, 11, [10].
Swertz, M. A., Dijkstra, M., Adamusiak, T., van der Velde, J. K., Kanterakis, A., Roos, E. T., Lops, J., Thorisson, G. A., Arends, D., Byelas, G., Muilu, J., Brookes, A. J., de Brock, E. O., Jansen, R. C., & Parkinson, H. (2010). The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button. Bmc Bioinformatics, 11 suppl 12 (S12), S12-1-S12-9. [12].
Swertz, M. A., van der Velde, K. J., Tesson, B. M., Scheltema, R. A., Arends, D., Vera, G., Alberts, R., Dijkstra, M., Schofield, P., Schughart, K., Hancock, J. M., Smedley, D., Wolstencroft, K., Goble, C., de Brock, E. O., Jones, A. R., Parkinson, H. E., & Jansen, R. C. (2010). XGAP: A uniform and extensible data model and software platform for genotype and phenotype experiments. Genome Biology, 11(3), [27].


Heap, G. A., Trynka, G., Jansen, R. C., Bruinenberg, M., Swertz, M. A., Dinesen, L. C., Hunt, K. A., Wijmenga, C., vanHeel, D. A., Franke, L., & Heel, D. A. V. (2009). Complex nature of SNP genotype effects on gene expression in primary human leucocytes. BMC Medical Genomics, 2(1), [1].
Jansen, R. C., Tesson, B. M., Fu, J., Yang, Y., McIntyre, L. M., & McInttyre, L. M. (2009). Defining gene and QTL networks. Current Opinion in Plant Biology, 12(2), 241-246.
Li, Y., Swertz, M. A., Vera, G., Fu, J., Breitling, R., & Jansen, R. C. (2009). designGG: an R-package and web tool for the optimal design of genetical genomics experiments. Bmc Bioinformatics, 10(188), [188].
Franke, L., & Jansen, R. C. (2009). eQTL Analysis in Humans. In K. DiPetrillo (Ed.), Cardiovascular Genomics: Methods and Protocols (Vol. 573, pp. 311-328). (Methods in Molecular Biology; No. 573). Springer.
Franke, L. H., & Jansen, R. C. (2009). eQTL Analysis in Humans in Methods in Molecular Biology. In Dipetrello (Ed.), Cardiovascular Genomics
Tesson, B. M., & Jansen, R. C. (2009). eQTL Analysis in Mice and Rats. In K. DiPetrillo (Ed.), Cardiovascular Genomics: Methods and Protocols (573 ed., pp. 285-309). (Methods in Molecular Biology; No. 573). Springer.
Tesson, B. M., & Jansen, R. C. (2009). eQTL Analysis in mice and rats Methods in Molecular Biology. In Dipetrello K. (Ed.), Cardiovascular Genetics
Gerrits, A., Li, Y., Tesson, B. M., Bystrykh, L. V., Weersing, E., Ausema, A., Dontje, B., Wang, X., Breitling, R., Jansen, R. C., de Haan, G., & Dethmers-Ausema, B. (2009). Expression Quantitative Trait Loci Are Highly Sensitive to Cellular Differentiation State. PLoS genetics, 5(10), [1000692].
Dijkstra, M., & Jansen, R. C. (2009). Optimal analysis of complex protein mass spectra. Proteomics, 9(15), 3869-3876.
Scheltema, R. A., Decuypere, S., Dujardin, J. C., Watson, D. G., Jansen, R. C., & Breitling, R. (2009). Simple data-reduction method for high-resolution LC-MS data in metabolomics. Bioanalysis, 1(9), 1551-1557.
Fu, J., Keurentjes, J. J. B., Bouwmeester, H., America, T., Verstappen, F. W. A., Ward, J. L., Beale, M. H., de Vos, R. C. H., Dijkstra, M., Scheltema, R. A., Johannes, F., Koornneef, M., Vreugdenhil, D., Breitling, R., & Jansen, R. C. (2009). System-wide molecular evidence for phenotypic buffering in Arabidopsis. Nature Genetics, 41(2), 166-167.


Alberts, R., Vera, G., & Jansen, R. C. (2008). affyGG: computational protocols for genetical genomics with Affymetrix arrays. Bioinformatics, 24(3), 433-434.
Johannes, F., Colot, V., & Jansen, R. C. (2008). Epigenome dynamics: a quantitative genetics perspective. Nature Reviews Genetics, 9, 883 - 890.
Li, Y., Breitling, R., & Jansen, R. C. (2008). Generalizing genetical genomics: getting added value from environmental perturbation. Trends in Genetics, 24(10), 518-524.
Breitling, R., Li, Y., Tesson, B. M., Fu, J., Wu, C., Wiltshire, T., Gerrits, A., Bystrykh, L. V., de Haan, G., Su, A. I., & Jansen, R. C. (2008). Genetical Genomics: Spotlight on QTL Hotspots. PLoS genetics, 4(10), [e1000232].
Scheltema, R. A., Kamleh, A., Wildridge, D., Ebikeme, C., Watson, D. G., Barrett, M. R., Jansen, R. C., Breitling, R., & Barrett, M. P. (2008). Increasing the mass accuracy of high-resolution LC-MS data using background ions - a case study on the LTQ-Orbitrap. Proteomics, 8(22), 4647-4656.
Johannes, F., Colot, V., & Jansen, R. C. (2008). OPINION Epigenome dynamics: a quantitative genetics perspective. Nature Reviews Genetics, 9(11), 883-890.
Lam, A. C., Fu, J., Jansen, R. C., Haley, C. S., & de Koning, D-J. (2008). Optimal Design of Genetic Studies of Gene Expression With Two-Color Microarrays in Outbred Crosses. Genetics, 180(3), 1691-1698.
Vera, G., Jansen, R. C., & Suppi, R. L. (2008). R/parallel - speeding up bioinformatics analysis with R. Bmc Bioinformatics, 22(9), 390. [390].
Swertz, M. A., Smedley, D., Wolstencroft, K., Alberts, R., Zouberakis, M., Aidinis, V., Schughart, K., Schofield, P. N., & Jansen, R. C. (2008). Towards dynamic database infrastructures for mouse genetics. In 8th IEEE International Conference on BioInformatics and BioEngineering, 2008. BIBE 2008 University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute (GBB).


Alberts, R., Terpstra, P., Hardonk, M., Bystrykh, L. V., de Haan, G., Breitling, R., Nap, J-P., & Jansen, R. C. (2007). A verification protocol for the probe sequences of Affymetrix genome arrays reveals high probe accuracy for studies in mouse, human and rat. Bmc Bioinformatics, 8(1), [132].
Nolte, I. M., Vries, A. R. D., Spijker, G. T., Jansen, R. C., Brinza, D., Zelikovsky, A., & Meerman, G. J. T. (2007). Association testing by haplotype-sharing methods applicable to whole-genome analysis. BMC Proceedings, 1 Suppl 1, S129.
Swertz, M. A., & Jansen, R. C. (2007). Beyond standardization: dynamic software infrastructures for systems biology. Nature Reviews Genetics, 8(3), 235-243.
Fu, J., Swertz, M. A., Keurentjes, J. J. B., & Jansen, R. C. (2007). MetaNetwork: A computational protocol for the genetic study of metabolic networks. Nature protocols, 2(3), 685-694.
Nyangoma, S. O., Van Kampen, A. A., Reijmers, T. H., Govorukhina, N. I., van der Zee, A. G., Billingham, I. J., Bischoff, R., & Jansen, R. C. (2007). Multiple testing issues in discriminating compound-related peaks and chromatograms from high frequency noise, spikes and solvent-based nois in LC-MS data sets. Statistical applications in genetics and molecular biology, 6(article 23).
Nyangoma, S. O., van Kampen, A. A. H. C., Reijmers, T. H., Govorukhina, N. I., van der Zee, A. G. J., Billingham, L. J., Bischoff, R., & Jansen, R. C. (2007). Multiple testing issues in discriminating compound-related peaks and chromatograms from high frequency noise, spikes and solvent-based noise in LC-MS data sets. Statistical applications in genetics and molecular biology, 6(1), [23].
Keurentjes, J. J. B., Fu, J., Terpstra, I. R., Garcia, J. M., Ackerveken, G. V. D., Snoek, L. B., Peeters, A. J. M., Vreugdenhil, D., Koornneef, M., & Jansen, R. C. (2007). Regulatory network construction in Arabidopsis by using genome-wide gene expression quantitative trait loci. Proceedings of the National Academy of Sciences of the United States of America, 104(5), 1708-1713.
Keurentjes, J. J. B., Fu, J. J., Terpstra, I. R., Garcia, J. M., van den Ackerveken, G., Snoek, L. B., Peeters, A. J. M., Vreugdenhil, D., Koornreef, M., & Jansen, R. C. (2007). Regulatory Network Construction in Arabidopsis using genome-wide gene expression QTLs. PNAS, 104, 1708 - 1713.
Dijkstra, M., Vonk, R., & Jansen, R. C. (2007). SELDI-TOF mass spectra: A view on sources of variation. Journal of Chromatography B, 847(1), 12-23.
Alberts, R., Terpstra, P., Li, Y., Breitling, R., Nap, J., & Jansen, R. C. (2007). Sequence Polymorphisms Cause Many False cis eQTLs. PLoS ONE, 2(7), 132 - 136. [622].


Govorukhina, N. I., Reijmers, T. H., Nyangoma, S. O., van der Zee, A. GJ., Jansen, R. C., & Bischoff, R. (2006). Analysis of human serum by liquid chromatography-mass spectrometry: Improved sample preparation and data analysis: Improved sample preparation and data analysis. Journal of Chromatography A, 1120(1-2), 142 - 150.
Nyangoma, S. O., Fung, W-K., & Jansen, R. C. (2006). Identifying influential multinomial observations by perturbation. Computational Statistics %26 Data Analysis, 50(10), 2799 - 2821.
Li, Y., Gutteling, E. W., Tijsterman, M., Fu, J., Riksen, J. A. G., Hazendonk, E., Prins, P., Plasterk, R. H. A., Jansen, R. C., Breitling, R., Kammenga, J. E., & Álvarez, O. A. (2006). Mapping determinants of gene expression plasticity by genetical genomics in C-elegans. PLoS genetics, 2(12), 2155 - 2161. [222].
Fu, J., & Jansen, R. C. (2006). Optimal Design and Analysis of Genetic Studies on Gene Expression. Genetics, 172(3), 1993-1999.
Dijkstra, M., Roelofsen, H., Vonk, R. J., & Jansen, R. C. (2006). Peak quantification in surface-enhanced laser desorption/ionization by using mixture models. Proteomics, 6(19), 5106 - 5116.
Albers, C. J., Jansen, R. C., Kok, J., Kuipers, O. P., & Hijum, S. A. F. T. V. (2006). SIMAGE: simulation of DNA-microarray gene expression data. Bmc Bioinformatics, 7(205), [205].
Keurentjes, J. J. B., Fu, J., Vos, C. H. R. D., Lommen, A., Hall, R. D., Bino, R. J., Plas, L. H. W. V. D., Jansen, R. C., Vreugdenhil, D., Koornneef, M., Hall, RD., Bino, RJ., & van der Plas, LHW. (2006). The genetics of plant metabolism. Nature Genetics, 38(7), 842 - 849.


Alberts, R., Terpstra, P., Bystrykh, L. V., Haan, G. D., & Jansen, R. C. (2005). A statistical multiprobe model for analyzing cis and trans genes in genetical genomics experiments with short-oligonucleotide arrays. Genetics, 171(3), 1437 - 1439.
Horvatovich, P., Govorukhina, N. I., Reijmers, T. H., Nyangoma, S., Jansen, R. C., & Bischoff, R. (2005). Biomarker discovery for the early diagnosis of cervical cancer. Febs Journal, 272, 494 - 495.
Alberts, R., Fu, J., Swertz, M. A., Lubbers, L. A., Albers, C. J., & Jansen, R. C. (2005). Combining microarrays and genetic analysis. Briefings in Bioinformatics, 6(2), 135-145.
Spijker, G. T., Nolte, I. M., Jansen, R. C., & te Meerman, G. J. (2005). Genetic association studies in complex disease: Disentangling additional predisposing loci from associated neutral loci using a constrained - permutation approach. Annals of Human Genetics, 69(1), 90 - 101.
de Haan, G., Bystrykh, L. V., Weersing, E., Sutton, S., Manly, K., Chesler, E., Jansen, R. C., Vellenga, E., Williams, R. W., & Cooke, M. P. (2005). Genetical genomics to identify gene networks in hematopoietic stem cells. Experimental Hematology, 33(7), 60 - 60.
Fu, J. J., & Jansen, R. C. (2005). Optimal Design and Analysis of Genetic Studies on Gene Expression. Genetics, 172, 1993 - 1999.
Bystrykh, L., Weersing, E., Dontje, B., Sutton, S., Pletcher, M. T., Wiltshire, T., Su, A. I., Vellenga, E., Wang, J., Manly, K. F., Lu, L., Chesler, E. J., Alberts, R., Jansen, R. C., Williams, R. W., Cooke, M., Pletcher, MT., de Haan, G., Su, AI., ... Williams, O. (2005). Uncovering regulatory pathways that effect hematopoietic stem cell function using 'genetical genomics'. Nature Genetics, 37(3), 225 - 232.


Swertz, M. A., Brock, E. O. B. D., Hijum, S. A. F. T. V., Jong, A. D., Buist, G., Baerends, R. J. S., Kok, J., Kuipers, O. P., & Jansen, R. C. (2004). Molecular Genetics Information System (MOLGENIS): alternatives in developing local experimental genomics databases. Bioinformatics, 20(13), 2075 - 2083.
Jansen, R. C., & Nap, J-P. (2004). Regulating gene expression: surprises still in store. Trends in Genetics, 20(5), 223 - 225.
Churchill, G. A., Jansen, R. C., Airey, D. C., Allayee, H., Angel, J. M., Attie, A. D., Beatty, J., Beavis, W. D., Belknap, J. K., Bennett, B., Berrettini, W., Bleich, A., Bogue, M., Broman, K. W., Buck, K. J., Buckler, E., Burmeister, M., Chesler, E. J., Cheverud, J. M., ... Complex Trait Consortium (2004). The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics, 36(11), 1133-1137.


Jansen, R. C. (2003). Levensecht puzzelen. s.n.
Jansen, R. C., Jannink, J-L., & Beavis, W. D. (2003). Mapping quantitative trait loci in plant breeding populations: Use of parental haplotype sharing. Crop Science, 43(3), 829-834.
Jansen, R. C. (2003). Studying complex biological systems using multifactorial perturbation. Nature Reviews Genetics, 4(2), 145-151.
Abiola, O., Angel, JM., Avner, P., Bachmanov, AA., Belknap, JK., Bennett, B., Blankenhorn, EP., Blizard, DA., Bolivar, N. V., Brockmann, GA., Buck, KJ., Bureau, JF., Casley, WL., Chesler, EJ., Cheverud, JM., Churchill, GA., Cook, M., Crabbe, JC., Crusio, WE., ... Complex Trait Consortium (2003). The nature and identification of quantitative trait loci: a community's view. Nature Reviews Genetics, 4(11), 911-916.


Boer, M. P., Braak, C. J. F. T., & Jansen, R. C. (2002). A penalized likelihood method for mapping epistatic quantitative trait loci with one-dimensional genome searches. Genetics, 162(2), 951-960.
Mlynárová, L., Loonen, A., Mietkiewska, E., Jansen, R. C., & Nap, J-P. (2002). Assembly of Two Transgenes in an Artificial Chromatin Domain Gives Highly Coordinated Expression in Tobacco. Genetics, 160, 727-740.
Balding, DJ., Carothers, AD., Marchini, JL., Cardon, LR., Vetta, A., Griffiths, B., Weir, BS., Hill, WG., Goldstein, D., Strimmer, K., Myers, S., Beaumont, MA., Glasbey, CA., Mayer, CD., Richardson, S., Marshall, C., Durrett, R., Nielsen, R., Visscher, PM., ... Gabrielson, E. (2002). Discussion on the meeting on 'Statistical modelling and analysis of genetic data'. Journal of the Royal Statistical Society. Series B: Statistical Methodology, 64, 737-775.
Jansen, R. C., Nap, J-P., & Mlynárová, L. (2002). Errors in genomics and proteomics. Nature Biotechnology, 20(19).
van Ooien, J. W., Boer, M. P., Jansen, R. C., & Maliepaard, C. (2002). MapQTL 4.0: Software For The Calculation Of QTL Positions On Genetic Maps. Plant Research International.
Bink, M. C. A. M., Uimari, P., Sillanpää, M. J., Janss, L. L. G., & Jansen, R. C. (2002). Multiple QTL mapping in related plant populations via a pedigree-analysis approach. Theoretical and Applied Genetics, 104(5), 751-762.


Jansen, R. C., Geerlings, H., Oeveren, A. J. V., & Schaik, R. C. V. (2001). A Comment on Codominant Scoring of AFLP Markers. Genetics.
Last modified:17 August 2020 08.44 a.m.
printView this page in: Nederlands