Professor of Medical Systems Biology & Rosalind Franklin Fellow
- Barbara Bakker studied (bio)chemistry at the University of Amsterdam and graduated cum laude in 1994.
- She did a PhD on the control and regulation of glucose metabolism in African trypanosomes, using computer modelling and experimentation. She graduated cum laude in 1998 at the Vrije Universiteit Amsterdam.
- 1998-2000 Postdoc Industrial Microbiology at the Delft University of Technology.
- 2000-2008 Assistant, then Associate Professor at the Vrije Universiteit Amsterdam, Department of Molecular Cell Physiology.
- 2012 Professor of Medical Systems Biology
Research Interests, from microbial to human Systems Biology
- Sofar her research has focussed on Systems Biology of yeast and African trypanosomes. Her group developed experimentally validated computer models of glucose metabolism and gene expression and made a contribution to the quantitative analysis of regulation (Regulation Analysis). She developed a strategy for drug target identification based on the quantitative analysis of metabolic networks.
- At the UMCG she will extend the Systems Biology approach to human metabolic diseases. Notably she will study the interplay between lipid and carbohydrate metabolism in order to develop predictive computer models for metabolic syndrome and inborn metabolic diseases.
- Via a small appointment at the Vrije Universiteit Amsterdam she is a member of the Netherlands Institute for Systems Biology (NISB) and the Kluyver Centre for Industrial Genomics.
Awards
Barbara received an NWO Vernieuwingsimpuls and the award of the Netherlands Society for Biochemistry and Molecular Biology (NVBMB).