prof. dr. R.P.H. (Rainer) Bischoff

Hoogleraar & hoofd afdeling analytische biochemie


Postal address:
A Deusinglaan
Gebouw 3226, ruimte 0601

Phone: +31 50 363 3338

Fax: +31 50 363 7582

Research interests


Prof. Dr. Rainer Bischoff

Chair of the Department of Analytical Biochemistry (


Faculty of Mathematics and Natural Science, University of Groningen, the Netherlands        

Telephone: +31 50 363 3336



Field/ Discipline: Chemistry, Analytical
                         Biochemical Research Methods

Expertise:          Proteomics, Chromatography, Mass 
                         Spectrometry, Electrochemistry
                         Biopharmaceuticals, Biomarkers   


Rainer Bischoff started his career in protein-related research when joining the biotechnology company Transgene (Strasbourg, France) in 1987. He applied mass spectrometry to the characterization of recombinant proteins early on with a first paper appearing in 1990 using electrospray ionization for the analysis of alpha-1-antitrypsin and its variants. Rainer Bischoff continued his career at AstraZeneca R&D (Lund, Sweden) before joining the Faculty of Mathematics and Natural Sciences at the University of Groningen (The Netherlands) in 2001 as full professor of Analytical Biochemistry. Research interests of the Analytical Biochemistry Department focus on biomarker discovery and validation, bioinformatics (in collaboration with Prof. Horvatovich), the bioanalysis of biopharmaceutical proteins and the development of novel instrumental analytical techniques (e.g. based on the coupling of electrochemistry to mass spectrometry). The group uses state-of-the-art equipment for protein and peptide separation and identification mainly based on high-performance liquid chromatography coupled to mass spectrometry. Rainer Bischoff is responsible for the interfaculty mass spectrometry core facility housing currently 16 LC-MS/MS installations.

Rainer Bischoff served in a number of functions such as chairing the national Analytical Chemistry working group of the Dutch Scientific Research Organization (NWO) and currently being the Dutch representative of the Chromosome-Centric HPP program of HUPO.

Rainer Bischoff authored more than 160 peer-reviewed publications and book chapters and is inventor on 12 patents.

Google Scholar:

ISI Researcher ID:


  1. Surface-modified electrodes in the mimicry of oxidative drug metabolism

    Research output: Scientific - peer-reviewArticle

  2. Antibody-free LC-MS/MS quantification of rhTRAIL in human and mouse serum

    Research output: Scientific - peer-reviewArticle

  3. Physiology and pathophysiology of matrix metalloproteases

    Research output: Scientific - peer-reviewArticle

View all (250) »


  1. Journal of Chromatography B (Journal)

    Activity: ScientificEditorial activity

View all (1) »

Press / Media

  1. Elektrochemische enzymen

    Press / Media: Research

  2. Elektrochemische Enzymen

    Press / Media: Research

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