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Publicaties

Thiostrepton induces cell death of acute myeloid leukemia blasts and the associated macrophage population

The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia

The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia

HUWE1 cooperates with RAS activation to control leukemia cell proliferation and human hematopoietic stem cells differentiation fate

HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells

Transcriptional regulators CITED2 and PU.1 cooperate in maintaining hematopoietic stem cells

Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones

BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells

Establishing human leukemia xenograft mouse models by implanting human bone marrow-like scaffold-based niches

Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation

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