Publication

Membrane-bound organelles versus membrane-less compartments and their control of anabolic pathways in Drosophila

Aguilera-Gomez, A. & Rabouille, C. 15-Aug-2017 In : Developmental Biology. 428, 2, p. 310-317 8 p.

Research output: Scientific - peer-reviewArticle

APA

Aguilera-Gomez, A., & Rabouille, C. (2017). Membrane-bound organelles versus membrane-less compartments and their control of anabolic pathways in Drosophila. Developmental Biology, 428(2), 310-317. DOI: 10.1016/j.ydbio.2017.03.029

Author

Aguilera-Gomez, Angelica; Rabouille, Catherine / Membrane-bound organelles versus membrane-less compartments and their control of anabolic pathways in Drosophila.

In: Developmental Biology, Vol. 428, No. 2, 15.08.2017, p. 310-317.

Research output: Scientific - peer-reviewArticle

Harvard

Aguilera-Gomez, A & Rabouille, C 2017, 'Membrane-bound organelles versus membrane-less compartments and their control of anabolic pathways in Drosophila' Developmental Biology, vol 428, no. 2, pp. 310-317. DOI: 10.1016/j.ydbio.2017.03.029

Standard

Membrane-bound organelles versus membrane-less compartments and their control of anabolic pathways in Drosophila. / Aguilera-Gomez, Angelica; Rabouille, Catherine.

In: Developmental Biology, Vol. 428, No. 2, 15.08.2017, p. 310-317.

Research output: Scientific - peer-reviewArticle

Vancouver

Aguilera-Gomez A, Rabouille C. Membrane-bound organelles versus membrane-less compartments and their control of anabolic pathways in Drosophila. Developmental Biology. 2017 Aug 15;428(2):310-317. Available from, DOI: 10.1016/j.ydbio.2017.03.029


BibTeX

@article{bcc9fce9e66242b8b23803e4417672b9,
title = "Membrane-bound organelles versus membrane-less compartments and their control of anabolic pathways in Drosophila",
abstract = "Classically, we think of cell compartmentalization as being achieved by membrane-bound organelles. It has nevertheless emerged that membrane-less assemblies also largely contribute to this compartmentalization. Here, we compare the characteristics of both types of compartmentalization in term of maintenance of functional identities. Furthermore, membrane less-compartments are critical for sustaining developmental and cell biological events as they control major metabolic pathways. We describe two examples related to this issue in Drosophila, the role of P-bodies in the translational control of gurken in the Drosophila oocyte, and the formation of Sec bodies upon amino-acid starvation in Drosophila cells.",
keywords = "Cell compartmentalization, Membrane-bound organelles, Membrane-less compartments, Liquid droplets, Liquid-liquid phase separation, Low complexity sequence, Secretory pathway, ER exit sites, gurken translation, Drosophila, Oocyte, Orb, S2 cells, COPII, Sec16, PARP16, Stress granule, mRNA, FMR1, GURKEN MESSENGER-RNA, CELL-FREE FORMATION, STRESS GRANULES, PHASE-SEPARATION, P-BODIES, COPII COAT, SECRETORY PATHWAY, ENDOPLASMIC-RETICULUM, AXIS DETERMINATION, PROCESSING BODIES",
author = "Angelica Aguilera-Gomez and Catherine Rabouille",
year = "2017",
month = "8",
doi = "10.1016/j.ydbio.2017.03.029",
volume = "428",
pages = "310--317",
journal = "Developmental Biology",
issn = "0012-1606",
publisher = "ACADEMIC PRESS INC ELSEVIER SCIENCE",
number = "2",

}

RIS

TY - JOUR

T1 - Membrane-bound organelles versus membrane-less compartments and their control of anabolic pathways in Drosophila

AU - Aguilera-Gomez,Angelica

AU - Rabouille,Catherine

PY - 2017/8/15

Y1 - 2017/8/15

N2 - Classically, we think of cell compartmentalization as being achieved by membrane-bound organelles. It has nevertheless emerged that membrane-less assemblies also largely contribute to this compartmentalization. Here, we compare the characteristics of both types of compartmentalization in term of maintenance of functional identities. Furthermore, membrane less-compartments are critical for sustaining developmental and cell biological events as they control major metabolic pathways. We describe two examples related to this issue in Drosophila, the role of P-bodies in the translational control of gurken in the Drosophila oocyte, and the formation of Sec bodies upon amino-acid starvation in Drosophila cells.

AB - Classically, we think of cell compartmentalization as being achieved by membrane-bound organelles. It has nevertheless emerged that membrane-less assemblies also largely contribute to this compartmentalization. Here, we compare the characteristics of both types of compartmentalization in term of maintenance of functional identities. Furthermore, membrane less-compartments are critical for sustaining developmental and cell biological events as they control major metabolic pathways. We describe two examples related to this issue in Drosophila, the role of P-bodies in the translational control of gurken in the Drosophila oocyte, and the formation of Sec bodies upon amino-acid starvation in Drosophila cells.

KW - Cell compartmentalization

KW - Membrane-bound organelles

KW - Membrane-less compartments

KW - Liquid droplets

KW - Liquid-liquid phase separation

KW - Low complexity sequence

KW - Secretory pathway

KW - ER exit sites

KW - gurken translation

KW - Drosophila

KW - Oocyte

KW - Orb

KW - S2 cells

KW - COPII

KW - Sec16

KW - PARP16

KW - Stress granule

KW - mRNA

KW - FMR1

KW - GURKEN MESSENGER-RNA

KW - CELL-FREE FORMATION

KW - STRESS GRANULES

KW - PHASE-SEPARATION

KW - P-BODIES

KW - COPII COAT

KW - SECRETORY PATHWAY

KW - ENDOPLASMIC-RETICULUM

KW - AXIS DETERMINATION

KW - PROCESSING BODIES

U2 - 10.1016/j.ydbio.2017.03.029

DO - 10.1016/j.ydbio.2017.03.029

M3 - Article

VL - 428

SP - 310

EP - 317

JO - Developmental Biology

T2 - Developmental Biology

JF - Developmental Biology

SN - 0012-1606

IS - 2

ER -

ID: 46989117