Publication

Consensus Guidelines for Implementing Pencil-Beam Scanning Proton Therapy for Thoracic Malignancies on Behalf of the PTCOG Thoracic and Lymphoma Subcommittee

Chang, J. Y., Zhang, X., Knopf, A., Li, H., Mori, S., Dong, L., Lu, H-M., Liu, W., Badiyan, S. N., Both, S., Meijers, A., Lin, L., Flampouri, S., Li, Z., Umegaki, K., Simone, C. B. & Zhu, X. R. 1-Sep-2017 In : INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 99, 1, p. 41-50 10 p.

Research output: Scientific - peer-reviewReview article

APA

Chang, J. Y., Zhang, X., Knopf, A., Li, H., Mori, S., Dong, L., ... Zhu, X. R. (2017). Consensus Guidelines for Implementing Pencil-Beam Scanning Proton Therapy for Thoracic Malignancies on Behalf of the PTCOG Thoracic and Lymphoma Subcommittee. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 99(1), 41-50. DOI: 10.1016/j.ijrobp.2017.05.014

Author

Chang, Joe Y.; Zhang, Xiaodong; Knopf, Antje; Li, Heng; Mori, Shinichiro; Dong, Lei; Lu, Hsiao-Ming; Liu, Wei; Badiyan, Shahed N.; Both, Stephen; Meijers, Arturs; Lin, Liyong; Flampouri, Stella; Li, Zuofeng; Umegaki, Kikuo; Simone, Charles B.; Zhu, Xiaorong R. / Consensus Guidelines for Implementing Pencil-Beam Scanning Proton Therapy for Thoracic Malignancies on Behalf of the PTCOG Thoracic and Lymphoma Subcommittee.

In: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, Vol. 99, No. 1, 01.09.2017, p. 41-50.

Research output: Scientific - peer-reviewReview article

Harvard

Chang, JY, Zhang, X, Knopf, A, Li, H, Mori, S, Dong, L, Lu, H-M, Liu, W, Badiyan, SN, Both, S, Meijers, A, Lin, L, Flampouri, S, Li, Z, Umegaki, K, Simone, CB & Zhu, XR 2017, 'Consensus Guidelines for Implementing Pencil-Beam Scanning Proton Therapy for Thoracic Malignancies on Behalf of the PTCOG Thoracic and Lymphoma Subcommittee' INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, vol 99, no. 1, pp. 41-50. DOI: 10.1016/j.ijrobp.2017.05.014

Standard

Consensus Guidelines for Implementing Pencil-Beam Scanning Proton Therapy for Thoracic Malignancies on Behalf of the PTCOG Thoracic and Lymphoma Subcommittee. / Chang, Joe Y.; Zhang, Xiaodong; Knopf, Antje; Li, Heng; Mori, Shinichiro; Dong, Lei; Lu, Hsiao-Ming; Liu, Wei; Badiyan, Shahed N.; Both, Stephen; Meijers, Arturs; Lin, Liyong; Flampouri, Stella; Li, Zuofeng; Umegaki, Kikuo; Simone, Charles B.; Zhu, Xiaorong R.

In: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, Vol. 99, No. 1, 01.09.2017, p. 41-50.

Research output: Scientific - peer-reviewReview article

Vancouver

Chang JY, Zhang X, Knopf A, Li H, Mori S, Dong L et al. Consensus Guidelines for Implementing Pencil-Beam Scanning Proton Therapy for Thoracic Malignancies on Behalf of the PTCOG Thoracic and Lymphoma Subcommittee. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2017 Sep 1;99(1):41-50. Available from, DOI: 10.1016/j.ijrobp.2017.05.014


BibTeX

@article{6800e022336643a08952583fa29ef5e1,
title = "Consensus Guidelines for Implementing Pencil-Beam Scanning Proton Therapy for Thoracic Malignancies on Behalf of the PTCOG Thoracic and Lymphoma Subcommittee",
abstract = "Pencil-beam scanning (PBS) proton therapy (PT), particularly intensity modulated PT, represents the latest advanced PT technology for treating cancers, including thoracic malignancies. On the basis of virtual clinical studies, PBS-PT appears to have great potential in its ability to tightly tailor the dose to the target while sparing critical structures, thereby reducing treatment-related toxicities, particularly for tumors in areas with complicated anatomy. However, implementing PBS-PT for moving targets has several additional technical challenges compared with intensity modulated photon radiation therapy or passive scattering PT. Four-dimensional computed tomographye based motion management and robust optimization and evaluation are crucial for minimizing uncertainties associated with beam range and organ motion. Rigorous quality assurance is required to validate dose delivery both before and during the course of treatment. Active motion management (eg, breath hold), beam gating, rescanning, tracking, or adaptive planning may be needed for cases involving significant motion or changes in motion or anatomy over the course of treatment. (C) 2017 The Authors. Published by Elsevier Inc.",
keywords = "CELL LUNG-CANCER, POLYMER GEL DOSIMETER, MOTION MITIGATION, RESPIRATORY MOTION, PARTICLE THERAPY, ROBUST OPTIMIZATION, RADIATION-THERAPY, MOVING TARGETS, TUMOR MOTION, TREATMENT UNCERTAINTIES",
author = "Chang, {Joe Y.} and Xiaodong Zhang and Antje Knopf and Heng Li and Shinichiro Mori and Lei Dong and Hsiao-Ming Lu and Wei Liu and Badiyan, {Shahed N.} and Stephen Both and Arturs Meijers and Liyong Lin and Stella Flampouri and Zuofeng Li and Kikuo Umegaki and Simone, {Charles B.} and Zhu, {Xiaorong R.}",
year = "2017",
month = "9",
doi = "10.1016/j.ijrobp.2017.05.014",
volume = "99",
pages = "41--50",
journal = "INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS",
issn = "0360-3016",
publisher = "ELSEVIER SCIENCE INC",
number = "1",

}

RIS

TY - JOUR

T1 - Consensus Guidelines for Implementing Pencil-Beam Scanning Proton Therapy for Thoracic Malignancies on Behalf of the PTCOG Thoracic and Lymphoma Subcommittee

AU - Chang,Joe Y.

AU - Zhang,Xiaodong

AU - Knopf,Antje

AU - Li,Heng

AU - Mori,Shinichiro

AU - Dong,Lei

AU - Lu,Hsiao-Ming

AU - Liu,Wei

AU - Badiyan,Shahed N.

AU - Both,Stephen

AU - Meijers,Arturs

AU - Lin,Liyong

AU - Flampouri,Stella

AU - Li,Zuofeng

AU - Umegaki,Kikuo

AU - Simone,Charles B.

AU - Zhu,Xiaorong R.

PY - 2017/9/1

Y1 - 2017/9/1

N2 - Pencil-beam scanning (PBS) proton therapy (PT), particularly intensity modulated PT, represents the latest advanced PT technology for treating cancers, including thoracic malignancies. On the basis of virtual clinical studies, PBS-PT appears to have great potential in its ability to tightly tailor the dose to the target while sparing critical structures, thereby reducing treatment-related toxicities, particularly for tumors in areas with complicated anatomy. However, implementing PBS-PT for moving targets has several additional technical challenges compared with intensity modulated photon radiation therapy or passive scattering PT. Four-dimensional computed tomographye based motion management and robust optimization and evaluation are crucial for minimizing uncertainties associated with beam range and organ motion. Rigorous quality assurance is required to validate dose delivery both before and during the course of treatment. Active motion management (eg, breath hold), beam gating, rescanning, tracking, or adaptive planning may be needed for cases involving significant motion or changes in motion or anatomy over the course of treatment. (C) 2017 The Authors. Published by Elsevier Inc.

AB - Pencil-beam scanning (PBS) proton therapy (PT), particularly intensity modulated PT, represents the latest advanced PT technology for treating cancers, including thoracic malignancies. On the basis of virtual clinical studies, PBS-PT appears to have great potential in its ability to tightly tailor the dose to the target while sparing critical structures, thereby reducing treatment-related toxicities, particularly for tumors in areas with complicated anatomy. However, implementing PBS-PT for moving targets has several additional technical challenges compared with intensity modulated photon radiation therapy or passive scattering PT. Four-dimensional computed tomographye based motion management and robust optimization and evaluation are crucial for minimizing uncertainties associated with beam range and organ motion. Rigorous quality assurance is required to validate dose delivery both before and during the course of treatment. Active motion management (eg, breath hold), beam gating, rescanning, tracking, or adaptive planning may be needed for cases involving significant motion or changes in motion or anatomy over the course of treatment. (C) 2017 The Authors. Published by Elsevier Inc.

KW - CELL LUNG-CANCER

KW - POLYMER GEL DOSIMETER

KW - MOTION MITIGATION

KW - RESPIRATORY MOTION

KW - PARTICLE THERAPY

KW - ROBUST OPTIMIZATION

KW - RADIATION-THERAPY

KW - MOVING TARGETS

KW - TUMOR MOTION

KW - TREATMENT UNCERTAINTIES

U2 - 10.1016/j.ijrobp.2017.05.014

DO - 10.1016/j.ijrobp.2017.05.014

M3 - Review article

VL - 99

SP - 41

EP - 50

JO - INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

T2 - INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

JF - INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

SN - 0360-3016

IS - 1

ER -

ID: 47026137