Targeted Gynaecologic Oncology (TARGON)

Organisational unit: Research programme

  1. 2017
  2. Edmondson, R. J., Crosbie, E. J., Nickkho-Amiry, M., Kaufmann, A., Stelloo, E., Nijman, H. W., ... Kitchener, H. C. (2017). Markers of the p53 pathway further refine molecular profiling in high-risk endometrial cancer: A TransPORTEC initiative. Gynecologic Oncology, 146(2), 327-333. DOI: 10.1016/j.ygyno.2017.05.014
  3. Verlaat, W., Snijders, P. J. F., Novianti, P. W., Wilting, S. M., De Strooper, L. M. A., Trooskens, G., ... Steenbergen, R. D. M. (2017). Genome-wide DNA Methylation Profiling Reveals Methylation Markers Associated with 3q Gain for Detection of Cervical Precancer and Cancer. Clinical Cancer Research, 23(14), 3813-3822. DOI: 10.1158/1078-0432.CCR-16-2641
  4. Cebula, M., Riehn, M., Hillebrand, U., Kratzer, R. F., Kreppel, F., Koutsoumpli, G., ... Wirth, D. (2017). TLR9-Mediated Conditioning of Liver Environment Is Essential for Successful Intrahepatic Immunotherapy and Effective Memory Recall. Molecular Therapy. DOI: 10.1016/j.ymthe.2017.06.018
  5. van Leeuwen, R. W. F., Jansman, F. G. A., Hunfeld, N. G., Peric, R., Reyners, A. K. L., Imholz, A. L. T., ... Mathijssen, R. H. J. (2017). Tyrosine Kinase Inhibitors and Proton Pump Inhibitors: An Evaluation of Treatment Options. Clinical Pharmacokinetics, 56(7), 683-688. DOI: 10.1007/s40262-016-0503-3
  6. Moghadasi, S., Grundeken, V., Janssen, L. A. M., Dijkstra, N. H., Rodríguez-Girondo, M., van Zelst-Stams, W. A. G., ... van Asperen, C. J. (2017). Performance of BRCA1/2 mutation prediction models in male breast cancer patients. Clinical Genetics. DOI: 10.1111/cge.13065
  7. Shimelis, H., Mesman, R. L. S., Von Nicolai, C., Ehlen, A., Guidugli, L., Martin, C., ... NBCS Collaborators (2017). BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer. Cancer Research, 77(11), 2789-2799. DOI: 10.1158/0008-5472.CAN-16-2568
  8. Flanagan, J. M., Wilson, A., Koo, C., Masrour, N., Gallon, J., Loomis, E., ... Brown, R. (2017). Platinum-Based Chemotherapy Induces Methylation Changes in Blood DNA Associated with Overall Survival in Patients with Ovarian Cancer. Clinical Cancer Research, 23(9), 2213-2222. DOI: 10.1158/1078-0432.CCR-16-1754
  9. Byrne, A. T., Alferez, D. G., Amant, F., Annibali, D., Arribas, J., Biankin, A. V., ... EurOPDX Consortium (2017). Interrogating open issues in cancer precision medicine with patient-derived xenografts. Nature reviews cancer, 17(4), 254-268. DOI: 10.1038/nrc.2016.140
  10. Kitson, S., Sivalingam, V. N., Bolton, J., McVey, R., Nickkho-Amiry, M., Powell, M. E., ... Crosbie, E. J. (2017). Ki-67 in endometrial cancer: Scoring optimization and prognostic relevance for window studies. Modern Pathology, 30(3), 459-468. DOI: 10.1038/modpathol.2016.203, 10.1038/modpathol.2016.203
  11. Koeneman, M. M., Kruse, A-J., Kooreman, L. F. S., zur Hausen, A., Hopman, A. H. N., Sep, S. J. S., ... Kruitwagen, R. F. M. P. (2017). Preliminary stop of the TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia (TOPIC) trial. BMC CANCER, 17. DOI: 10.1186/s12885-017-3108-9
  12. Elst , van der, K. C. M., Veringa, A., Zijlstra, J. G., Beishuizen, A., Klont, R., Brummelhuis-Visser, P., ... Alffenaar, J-W. C. (2017). Low Caspofungin Exposure in Patients in Intensive Care Units. Antimicrobial Agents and Chemotherapy, 61(2), [ARTN e01582-16]. DOI: 10.1128/AAC.01582-16
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