Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI)

Organisational unit: Research programme

  1. 2017
  2. Dejaco, C., Brouwer, E., Mason, J. C., Buttgereit, F., Matteson, E. L., & Dasgupta, B. (2017). Giant cell arteritis and polymyalgia rheumatica: current challenges and opportunities. NATURE REVIEWS RHEUMATOLOGY, 13(10), 578-592. DOI: 10.1038/nrrheum.2017.142
  3. Henriksen, E. K. K., Viken, M. K., Wittig, M., Holm, K., Folseraas, T., Mucha, S., ... UK-PSC Consortium (2017). HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry. HLA, 90(4), 228-233. DOI: 10.1111/tan.13076
  4. Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., ... Kutalik, Z. (2017). CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits. Nature Communications, 8(1), [744]. DOI: 10.1038/s41467-017-00556-x
  5. Wheeler, E., Leong, A., Liu, C-T., Hivert, M-F., Strawbridge, R. J., Podmore, C., ... Lifelines Cohort Study (2017). Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLOS MEDICINE, 14(9), [1002383]. DOI: 10.1371/journal.pmed.1002383
  6. de Jong, M. J., van der Meulen-de Jong, A. E., Romberg-Camps, M. J., Becx, M. C., Maljaars, J. P., Cilissen, M., ... Pierik, M. J. (2017). Telemedicine for management of inflammatory bowel disease (myIBDcoach): A pragmatic, multicentre, randomised controlled trial. The Lancet, 390(10098), 959-968. DOI: 10.1016/S0140-6736(17)31327-2
  7. COIN study group, & Dutch Initiative on Crohn and Colitis (2017). Clinical Predictors of Future Nonadherence in Inflammatory Bowel Disease. Inflammatory Bowel Diseases, 23(9), 1568-1576. DOI: 10.1097/MIB.0000000000001201
  8. Kreiner, E., Waage, J., Standl, M., Brix, S., Pers, T. H., Couto Alves, A., ... Bønnelykke, K. (2017). Shared genetic variants suggest common pathways in allergy and autoimmune diseases. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 140(3), 771-781. DOI: 10.1016/j.jaci.2016.10.055
  9. Timmerman, H. M., Rutten, N. B. M. M., Boekhorst, J., Saulnier, D. M., Kortman, G. A. M., Contractor, N., ... Rijkers, G. T. (2017). Intestinal colonisation patterns in breastfed and formula-fed infants during the first 12 weeks of life reveal sequential microbiota signatures. Scientific Reports, 7, [8327]. DOI: 10.1038/s41598-017-08268-4
  10. Sydor, S., Manka, P., Best, J., Jafoui, S., Sowa, J-P., Zoubek, M. E., ... Bechmann, L. P. (2017). Kruppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury. Scientific Reports, 7(1), [8119]. DOI: 10.1038/s41598-017-08680-w
  11. Alberts, R., de Vries, E. M. G., Goode, E. C., Jiang, X., Sampaziotis, F., Rombouts, K., ... International PSC Study Group, The UK PSC Consortium (2017). Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Gut. DOI: 10.1136/gutjnl-2016-313598
  12. de Vries, F. E. E., Reeskamp, L. F., van Ruler, O., van Arum, I., Kuin, W., Dijksta, G., ... Serlie, M. J. (2017). Systematic review: pharmacotherapy for high-output enterostomies or enteral fistulas. Alimentary Pharmacology & Therapeutics, 46(3), 266-273. DOI: 10.1111/apt.14136
  13. Stone, J. H., Tuckwell, K., Dimonaco, S., Klearman, M., Aringer, M., Blockmans, D., ... Collinson, N. (2017). Trial of Tocilizumab in Giant-Cell Arteritis. New England Journal of Medicine, 377(4), 317-328. DOI: 10.1056/NEJMoa1613849
  14. de Vries, E. M., Wang, J., Williamson, K. D., Leeflang, M. M., Boonstra, K., Weersma, R. K., ... Ponsioen, C. Y. (2017). A novel prognostic model for transplant-free survival in primary sclerosing cholangitis. Gut. DOI: 10.1136/gutjnl-2016-313681
  15. Huang, H., Fang, M., Jostins, L., Umićević Mirkov, M., Boucher, G., Anderson, C. A., ... International Inflammatory Bowel Disease Genetics Consortium (2017). Fine-mapping inflammatory bowel disease loci to single-variant resolution. Nature, 547(7662), 173-178. DOI: 10.1038/nature22969
  16. Day, F. R., Thompson, D. J., Helgason, H., Chasman, D. I., Finucane, H., Sulem, P., ... PRACTICAl Consortium (2017). Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nature Genetics, 49(6), 834-841. DOI: 10.1038/ng.3841
  17. Weismueller, T. J., Trivedi, P. J., Bergquist, A., Imam, M., Lenzen, H., Ponsioen, C. Y., ... Int PSC Study Grp (2017). Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis. Gastroenterology, 152(8), 1975-1984. DOI: 10.1053/j.gastro.2017.02.038
  18. Tripathi, S. K., Chen, Z., Larjo, A., Kanduri, K., Nousiainen, K., Aijo, T., ... Lahesmaa, R. (2017). Genome-wide Analysis of STAT3-Mediated Transcription during Early Human Th17 Cell Differentiation. Cell reports, 19(9), 1888-1901. DOI: 10.1016/j.celrep.2017.05.013
  19. Tang, A. T., Hoi, J. P. C., Kotzin, J. J., Yang, Y., Hong, C. C., Hobson, N., ... Kahn, M. L. (2017). Endothelial TLR4 and the microbiome drive cerebral cavernous malformations. Nature, 545(7654), 305-310. DOI: 10.1038/nature22075
  20. Johansson, L. F., de Boer, E. N., de Weerd, H. A., van Dijk, F., Elferink, M. G., Schuring-Blom, G. H., ... Sikkema-Raddatz, B. (2017). Novel Algorithms for Improved Sensitivity in Non-Invasive Prenatal Testing. Scientific Reports, 7(1), [1838]. DOI: 10.1038/s41598-017-02031-5
  21. Wild, P. S., Felix, J. F., Schillert, A., Teumer, A., Chen, M-H., Leening, M. J. G., ... KNHI Investigators (2017). Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. CLIN Journal, 127(5), 1798-1812. DOI: 10.1172/JCI84840
  22. Gorski, M., Van der Most, P. J., Teumer, A., Chu, A. Y., Li, M., Mijatovic, V., ... Fuchsberger, C. (2017). 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Scientific Reports, 7, [45040]. DOI: 10.1038/srep45040
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