PhD ceremony: M.R. Nejadnik, 13.15 uur, Academiegebouw, Broerstraat 5, Groningen
Thesis: Polymer brush-coatings to prevent biomaterials associated infection. Initial bacterial adhesion and biofilm formation
Promotor(s): prof. H.J. Busscher, prof. W. Norde, prof. H.C. van der Mei
Faculty: Medical Sciences
Biomaterials associated infection (BAI) is one of the main causes of implant failure in an era in which the number of patients requiring biomaterials implant surgery is steadily increasing. Treatment of infected implants frequently includes long-term antibiotic use, however, often without success, so that finally the implant has to be removed. This thesis shows that brush-coatings are currently the most promising non-adhesive coatings that yield significant reductions, exceeding 90%, in microbial adhesion.
